How do you get your potassium? Potassium Sparing Diuretics
"Some EAT bananas" (as in some people eat bananas to get potassium? Maybe? No?)
Spironolactone, Eplerenone, Amiloride, Triamterene
Background: act in the distal collecting tubules
S and E: block the cytoplasmic steroid receptor for aldosterone.
A and T: block the sodium channel (ENaC) that is upregulated by aldosterone
By the way, the aldosterone receptor is a zinc finger. It'll go into the nucleus and bind DNA to induce transcription. Did you know that? Probably not that high yield, but it's important to remember to tie concepts like that together!
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