Wiskott-Aldrich and CGD

Wiskott-Aldrich Syndrome

Think "WAX TIE"

WA: Wiskott-Aldritch

X: X-linked Recessive

T: Thrombocytopenia

I: Infections

E: Eczema

Also, this helps with the immunoglobulins present:

WAX TIE... decreased IgM (think of the W as an upside down M, suggesting a decreased IgM), Increased IgA, Increased IgE

Chronic Granulomatous Disease

I don't have much to say about this, it's lack of NADPH oxidase, leading to increased infections to microbes that have catalase. So what are the catalase organisms? There are questions that are tricky, giving you names of organisms that you don't normally think about. Really, nocardia, aspergillus, and pseudomonas capecia are high yield (since they usually won't give you Staph aureus). So for the catalase positive organisms, remember this:

SNAPE

Staph aureus

Nocardia

Aspergillus

Pseudomonas (capeciae)

E. coli... or generally, Enterobactericiae

Check out my mnemonic on Enterobactericiae if you want to go even more detailed.